Basic Information
ID: ALA4613059
Type: Binding
Description: Inhibition of EED ( 1 to 441 residues) (unknown origin) pre-incubated for 15 mins before biotin-H3K27me3 (19 to 33 residues) addition and further incubated for 30 mins by AlphaScreen.based EED-H3K27me3 peptide competition binding assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Polycomb protein EED(ALA2189117)
Document: ALA4610126
Inhibition of EED ( 1 to 441 residues) (unknown origin) pre-incubated for 15 mins before biotin-H3K27me3 (19 to 33 residues) addition and further incubated for 30 mins by AlphaScreen.based EED-H3K27me3 peptide competition binding assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4613059
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 369.41 | 2.40 | 2.40 |
| 290.33 | 3.60 | 3.60 |
| 453.50 | 3.19 | 3.19 |
| 549.65 | 2.49 | 2.49 |
| 372.43 | 4.19 | 4.19 |
| 473.57 | 3.02 | 3.02 |
| 467.53 | 3.50 | 3.50 |
| 420.44 | 4.33 | 4.33 |
| 489.48 | 3.82 | 3.82 |
| 416.44 | 3.91 | 3.91 |
| 417.44 | 3.44 | 3.44 |
| 479.54 | 3.76 | 3.76 |
| 414.47 | 4.12 | 4.12 |
| 414.47 | 4.12 | 4.12 |
| 428.39 | 5.10 | 5.10 |
| 507.47 | 3.90 | 3.90 |
| 487.56 | 2.54 | 2.54 |
| 517.56 | 2.28 | 2.28 |
| 438.48 | 3.49 | 3.49 |
| 442.48 | 2.22 | 2.22 |
| 494.57 | 2.11 | 2.11 |
| 456.47 | 3.63 | 3.63 |
| 420.44 | 4.33 | 4.33 |
| 521.50 | 4.21 | 4.21 |
| 453.50 | 3.19 | 3.19 |
| 516.58 | 2.89 | 2.89 |
| 432.46 | 4.26 | 4.26 |
| 420.44 | 4.33 | 4.33 |
| 362.39 | 3.78 | 3.78 |
| 446.50 | 2.71 | 2.71 |
| 347.38 | 2.96 | 2.96 |
| 436.43 | 4.33 | 4.33 |
| 530.60 | 3.20 | 3.20 |
| 402.45 | 4.19 | 4.19 |
| 523.61 | 1.96 | 1.96 |