Assay Report Card

Basic Information

ID: ALA4613790

Type: Functional

Description: Inhibition of PGL1 synthesis in Mycobacterium leprae infected Swiss Webster mouse macrophages assessed as decrease in [U-14C]PA incorporation at 2 uM preincubated for 4 days post infection followed by [U-14C]PA addition and measured after 7 days by liquid scintillation counter analysis relative to control

Organism: Mycobacterium leprae

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
248.311.681.68
473.417.497.49
822.954.344.34
166.251.281.28
847.024.624.62
542.517.577.57
544.537.817.81