Assay Report Card

Basic Information

ID: ALA4613792

Type: Functional

Description: Inhibition of PGL1 synthesis in Mycobacterium leprae infected Swiss Webster mouse macrophages assessed as decrease in [U-14C]PA incorporation at 0.2 uM preincubated for 4 days post infection followed by [U-14C]PA addition and measured after 7 days by liquid scintillation counter analysis relative to control

Organism: Mycobacterium leprae

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
473.417.497.49
847.024.624.62
542.517.577.57
544.537.817.81