Basic Information
ID: ALA4613793
Type: Functional
Description: Antiinflammatory activity in human monocytes assessed as inhibition of LPS-induced TNFaplha production at 50 uM preincubated for 15 mins followed by LPS addition and measured after 4 hrs by ELISA relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Monocyte
Target: Monocyte(ALA614076)
Document: ALA4613212
Antiinflammatory activity in human monocytes assessed as inhibition of LPS-induced TNFaplha production at 50 uM preincubated for 15 mins followed by LPS addition and measured after 4 hrs by ELISA relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4613793
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 258.23 | 0.09 | 0.09 |
| 257.20 | 0.69 | 0.69 |
| 377.36 | 1.71 | 1.71 |
| 422.35 | 1.62 | 1.62 |
| 329.17 | 1.24 | 1.24 |
| 378.30 | 1.23 | 1.23 |
| 449.32 | 2.27 | 2.27 |
| 259.21 | 2.77 | 2.77 |
| 331.17 | 3.32 | 3.32 |
| 129.11 | 1.55 | 1.55 |
| 383.40 | 1.84 | 1.84 |
| 405.26 | 1.88 | 1.88 |