Basic Information
ID: ALA4613993
Type: ADME
Description: Inhibition of recombinant human C-terminal 4His-tagged CYP46A1 delta(2 to 50) mutant expressed in Escherichia coli at 60 to 100 uM using cholesterol as substrate measured after 30 mins in presence of cytochrome P450 oxidoreductase by gas chromatography-mass spectrometry
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4613993
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 331.68 | 3.78 | 3.78 |
| 331.68 | 3.78 | 3.78 |
| 315.68 | 4.07 | 4.07 |
| 317.69 | 4.46 | 4.46 |
| 313.71 | 3.90 | 3.90 |
| 315.72 | 4.30 | 4.30 |
| 331.68 | 3.78 | 3.78 |