Basic Information
ID: ALA4614753
Type: Binding
Description: Inhibition of serine protease factor B in 50% human whole blood assessed as reduction in alternative pathway-mediated membrane attack complex formation pre-incubated for 15 mins before activated zymosan A stimulation for 50 mins by ELISA
Format: BAO_0000221
Organism: Homo sapiens
Tissue: Blood
Target: Complement factor B(ALA5731)
Document: ALA4613250
Inhibition of serine protease factor B in 50% human whole blood assessed as reduction in alternative pathway-mediated membrane attack complex formation pre-incubated for 15 mins before activated zymosan A stimulation for 50 mins by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4614753
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 422.53 | 4.93 | 4.93 |
| 408.50 | 4.54 | 4.54 |
| 432.56 | 5.79 | 5.79 |
| 418.54 | 5.40 | 5.40 |
| 406.53 | 5.23 | 5.23 |
| 362.47 | 5.21 | 5.21 |
| 392.50 | 4.84 | 4.84 |