Basic Information
ID: ALA4615154
Type: Binding
Description: Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induced calcium influx pre-incubated for 30 mins before ATP stimulation by FLIPR assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4615154
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 525.68 | 2.95 | 2.95 |
| 349.23 | 4.68 | 4.68 |
| 383.68 | 5.34 | 5.34 |
| 272.69 | 3.17 | 3.17 |
| 315.68 | 4.32 | 4.32 |
| 1505.11 | ||
| 214.22 | 2.04 | 2.04 |
| 292.68 | 3.21 | 3.21 |
| 292.68 | 3.21 | 3.21 |
| 282.13 | 3.95 | 3.95 |
| 282.13 | 3.95 | 3.95 |
| 315.68 | 4.32 | 4.32 |
| 281.23 | 3.66 | 3.66 |
| 275.74 | 3.91 | 3.91 |
| 271.70 | 3.28 | 3.28 |
| 272.69 | 3.17 | 3.17 |
| 303.79 | 4.60 | 4.60 |
| 316.57 | 4.60 | 4.60 |
| 283.66 | 3.58 | 3.58 |
| 265.67 | 3.44 | 3.44 |
| 367.68 | 5.63 | 5.63 |
| 333.23 | 4.98 | 4.98 |
| 363.26 | 4.99 | 4.99 |
| 367.22 | 4.82 | 4.82 |
| 379.26 | 4.69 | 4.69 |
| 394.23 | 4.59 | 4.59 |
| 397.70 | 5.64 | 5.64 |
| 367.68 | 5.63 | 5.63 |
| 369.69 | 5.70 | 5.70 |
| 383.68 | 5.34 | 5.34 |
| 419.73 | 4.88 | 4.88 |
| 397.70 | 5.01 | 5.01 |
| 315.68 | 4.32 | 4.32 |
| 399.29 | 5.84 | 5.84 |
| 383.68 | 5.34 | 5.34 |
| 383.68 | 5.34 | 5.34 |
| 394.23 | 4.59 | 4.59 |
| 348.25 | 4.56 | 4.56 |
| 404.31 | 5.41 | 5.41 |
| 307.73 | 3.32 | 3.32 |
| 355.24 | 3.62 | 3.62 |
| 365.23 | 4.39 | 4.39 |
| 292.32 | 1.29 | 1.29 |
| 331.68 | 4.20 | 4.20 |
| 350.22 | 4.08 | 4.08 |
| 350.22 | 4.08 | 4.08 |
| 349.23 | 4.68 | 4.68 |
| 360.68 | 4.22 | 4.22 |
| 401.23 | 6.00 | 6.00 |
| 363.26 | 4.99 | 4.99 |
| 360.68 | 4.22 | 4.22 |
| 292.13 | 3.41 | 3.41 |
| 397.70 | 5.36 | 5.36 |
| 350.22 | 4.08 | 4.08 |
| 365.23 | 4.39 | 4.39 |
| 279.68 | 2.71 | 2.71 |
| 367.22 | 4.82 | 4.82 |
| 397.70 | 5.38 | 5.38 |
| 252.27 | 3.13 | 3.13 |
| 327.12 | 3.86 | 3.86 |
| 337.68 | 3.11 | 3.11 |
| 378.23 | 4.88 | 4.88 |
| 264.28 | 3.19 | 3.19 |
| 379.74 | 3.59 | 3.59 |
| 363.26 | 4.47 | 4.47 |