Basic Information
ID: ALA4615866
Type: Binding
Description: Inhibition of RNase H activity of recombinant His-tagged HIV-1 group M subtype B reverse transcriptase p66/p51 expressed in Escherichia coli M15 using 18-nucleotide 3'-fluorescein-labeled RNA/5'-dabcyl-labeled DNA hybrid as substrate incubated for 1 hr
Format: BAO_0000019
Organism: HIV-1 M:B
Target: Human immunodeficiency virus type 1 reverse transcriptase(ALA247)
Document: ALA4613295
Inhibition of RNase H activity of recombinant His-tagged HIV-1 group M subtype B reverse transcriptase p66/p51 expressed in Escherichia coli M15 using 18-nucleotide 3'-fluorescein-labeled RNA/5'-dabcyl-labeled DNA hybrid as substrate incubated for 1 hr: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4615866
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 126.11 | 0.42 | 0.42 |
| 188.19 | 1.77 | 1.77 |
| 216.24 | 2.25 | 2.25 |
| 393.41 | 4.53 | 4.53 |
| 205.22 | 1.58 | 1.58 |
| 281.31 | 3.25 | 3.25 |
| 393.45 | 5.44 | 5.44 |
| 582.59 | 5.63 | 5.63 |
| 285.28 | 2.76 | 2.76 |
| 517.56 | 7.16 | 7.16 |
| 267.29 | 2.78 | 2.78 |
| 154.17 | 0.89 | 0.89 |
| 554.53 | 5.15 | 5.15 |
| 537.64 | 7.31 | 7.31 |
| 177.16 | 1.10 | 1.10 |
| 264.28 | 3.44 | 3.44 |
| 545.61 | 7.64 | 7.64 |
| 541.65 | 7.85 | 7.85 |
| 385.47 | 5.27 | 5.27 |
| 510.53 | 5.45 | 5.45 |
| 292.34 | 3.92 | 3.92 |
| 569.71 | 8.33 | 8.33 |
| 542.60 | 6.46 | 6.46 |
| 549.63 | 8.18 | 8.18 |
| 509.58 | 6.83 | 6.83 |
| 361.38 | 4.43 | 4.43 |
| 253.26 | 2.77 | 2.77 |
| 523.61 | 7.22 | 7.22 |
| 313.33 | 3.24 | 3.24 |
| 439.49 | 6.06 | 6.06 |
| 389.43 | 4.91 | 4.91 |
| 577.68 | 8.66 | 8.66 |
| 538.58 | 5.93 | 5.93 |
| 295.34 | 3.26 | 3.26 |
| 413.52 | 5.74 | 5.74 |
| 421.50 | 5.92 | 5.92 |
| 570.65 | 6.94 | 6.94 |
| 467.50 | 6.01 | 6.01 |
| 551.66 | 7.70 | 7.70 |
| 411.44 | 5.58 | 5.58 |
| 495.55 | 6.49 | 6.49 |