Basic Information
ID: ALA4615967
Type: Binding
Description: Inhibition of GLI1 transcriptional activity in HH-responsive mouse NIH3T3 cells assessed as reduction in GLI1 protein expression at 5 uM incubated for 48 hrs in presence of SAG by Western blot analysis
Organism: Mus musculus
Cell type: NIH3T3
Activity Charts
Bioactivity
Activity Types for Assay ALA4615967
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 410.47 | 5.09 | 5.09 |
| 356.38 | 3.52 | 3.52 |
| 334.37 | 3.61 | 3.61 |
| 450.53 | 6.17 | 6.17 |
| 382.41 | 4.35 | 4.35 |
| 449.79 | 5.23 | 5.23 |
| 511.86 | 6.44 | 6.44 |
| 542.83 | 6.04 | 6.04 |
| 547.89 | 7.28 | 7.28 |
| 487.79 | 5.72 | 5.72 |
| 532.28 | 6.78 | 6.78 |
| 442.47 | 5.28 | 5.28 |
| 511.86 | 6.44 | 6.44 |
| 412.44 | 4.58 | 4.58 |
| 435.76 | 4.84 | 4.84 |
| 384.39 | 3.80 | 3.80 |
| 576.73 | 6.89 | 6.89 |
| 426.40 | 4.82 | 4.82 |
| 432.47 | 5.39 | 5.39 |
| 497.83 | 6.13 | 6.13 |
| 386.36 | 3.20 | 3.20 |
| 511.86 | 6.44 | 6.44 |
| 386.40 | 4.01 | 4.01 |