Basic Information
ID: ALA4616006
Type: Binding
Description: Inhibition of full length human N-terminal GST-tagged TNKS1 ADP-ART catalytic domain (1001 to 1327 residues) using histone H2A as substrate incubated for 20 mins followed by [32P[-NAD+ addition and further incubated for 1 hr by liquid scintillation counter
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4616006
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 295.34 | 2.18 | 2.18 |
| 409.45 | 3.80 | 3.80 |
| 367.48 | 2.23 | 2.23 |
| 547.68 | 2.66 | 2.66 |
| 494.65 | 2.66 | 2.66 |
| 424.53 | 2.97 | 2.97 |
| 500.67 | 4.77 | 4.77 |
| 476.61 | 3.32 | 3.32 |