Basic Information
ID: ALA4617454
Type: Binding
Description: Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [gamma-33P]ATP by radiometric scintillation assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4617454
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 349.42 | 3.58 | 3.58 |
| 364.43 | 3.16 | 3.16 |
| 418.48 | 4.07 | 4.07 |
| 425.51 | 5.24 | 5.24 |
| 388.45 | 4.06 | 4.06 |
| 394.46 | 3.17 | 3.17 |
| 388.45 | 4.06 | 4.06 |
| 388.45 | 4.06 | 4.06 |
| 387.46 | 4.66 | 4.66 |
| 402.40 | 4.17 | 4.17 |
| 381.44 | 4.60 | 4.60 |
| 382.42 | 4.00 | 4.00 |
| 349.42 | 3.58 | 3.58 |
| 379.44 | 3.59 | 3.59 |
| 383.45 | 4.44 | 4.44 |
| 363.44 | 3.89 | 3.89 |
| 364.43 | 3.16 | 3.16 |
| 376.42 | 4.19 | 4.19 |
| 382.42 | 4.00 | 4.00 |
| 383.86 | 4.23 | 4.23 |
| 418.48 | 4.07 | 4.07 |
| 426.42 | 5.07 | 5.07 |
| 364.43 | 3.16 | 3.16 |
| 352.39 | 3.29 | 3.29 |
| 367.40 | 3.72 | 3.72 |
| 394.46 | 3.17 | 3.17 |