Assay Report Card

Basic Information

ID: ALA4618180

Type: Binding

Description: Inhibition of GAL4-fused survivin DBD-survivin VP16 activation domain (unknown origin) homodimerization transfected in human DU145 cells assessed as reduction in SEAP reporter expression measured after 24 hrs by mammalian two hybrid assay

Organism: Homo sapiens

Cell type: DU-145

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
524.776.196.19
469.473.773.77
448.403.463.46
348.365.405.40
469.464.784.78
504.895.645.64
424.597.717.71
402.394.494.49
560.364.464.46
358.384.764.76
368.486.356.35