Basic Information
ID: ALA4618213
Type: Binding
Description: Protac activity at VHL1/SHP2 in human KYSE520 cells assessed as induction of SHP2 degradation at 0.1 uM measured after 6 hrs by Western blot analysis relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4618213
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1032.78 | ||
| 1129.94 | ||
| 1124.88 | ||
| 1124.83 | ||
| 1115.91 | ||
| 962.64 | 5.21 | 5.21 |
| 1088.89 | ||
| 1130.93 | ||
| 1074.86 | ||
| 1115.96 | ||
| 1094.80 | ||
| 1046.81 | ||
| 1059.89 | ||
| 990.70 | 5.99 | 5.99 |
| 1060.83 | ||
| 1101.93 | ||
| 976.67 | 5.60 | 5.60 |
| 1102.91 | ||
| 1074.86 | ||
| 1018.75 | ||
| 1004.72 | ||
| 948.62 | 4.82 | 4.82 |
| 1080.78 |