Assay Report Card

Basic Information

ID: ALA4618216

Type: Binding

Description: Protac activity at VHL1/SHP2 in human MV4-11 cells assessed as induction of SHP2 degradation at 0.1 uM measured after 24 hrs by Western blot analysis relative to control

Organism: Homo sapiens

Cell type: MV4-11

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1129.94
1124.88
1124.83
1115.91
1130.93
1115.96
1094.80
1059.89
1101.93
1080.78