Basic Information
ID: ALA4618345
Type: Binding
Description: Inhibition of recombinant N-terminal GST-fused human NIK (319 to 947 residues) expressed in baculovirus expression system incubated for 120 mins in presence of ATP by ADP-glo based luminescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4618345
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 397.89 | 3.12 | 3.12 |
| 421.51 | 3.60 | 3.60 |
| 549.68 | 3.03 | 3.03 |
| 457.56 | 2.97 | 2.97 |
| 473.61 | 3.56 | 3.56 |
| 417.51 | 3.58 | 3.58 |
| 445.55 | 2.83 | 2.83 |
| 446.54 | 3.25 | 3.25 |
| 404.50 | 3.48 | 3.48 |
| 459.58 | 3.22 | 3.22 |
| 529.67 | 3.72 | 3.72 |
| 448.55 | 3.50 | 3.50 |
| 463.54 | 4.00 | 4.00 |
| 406.49 | 3.67 | 3.67 |
| 403.49 | 3.19 | 3.19 |
| 487.59 | 3.09 | 3.09 |
| 377.45 | 2.66 | 2.66 |
| 446.54 | 3.25 | 3.25 |
| 430.54 | 4.02 | 4.02 |
| 447.52 | 2.65 | 2.65 |
| 479.99 | 4.51 | 4.51 |
| 445.55 | 3.86 | 3.86 |
| 473.61 | 3.56 | 3.56 |
| 461.55 | 3.98 | 3.98 |
| 361.43 | 3.42 | 3.42 |
| 422.51 | 2.35 | 2.35 |
| 463.59 | 3.99 | 3.99 |
| 537.67 | 2.89 | 2.89 |
| 459.58 | 3.17 | 3.17 |
| 446.54 | 3.25 | 3.25 |
| 465.54 | 2.84 | 2.84 |
| 431.54 | 3.83 | 3.83 |
| 459.58 | 3.22 | 3.22 |
| 445.55 | 3.86 | 3.86 |
| 474.59 | 3.89 | 3.89 |
| 461.60 | 3.42 | 3.42 |