Assay Report Card

Basic Information

ID: ALA4618402

Type: Functional

Description: Suppression of epidermal and dermal cell proliferation in C57 mouse model of IMQ-induced psoriasis assessed as reduction in Ki67 expression in back skin psoriatic lesions at 120 mg/kg, ig administered starting from day 3 post IMQ-challenge and measured 2 days post-last dose of IMQ by immunohistochemical analysis relative to control

Organism: Mus musculus

Strain: C57

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
446.543.253.25