Basic Information
ID: ALA4618407
Type: Functional
Description: In vivo inhibition of NIK in C57 mouse model of IMQ-induced psoriasis assessed as reduction in NF-kappaB signalling in back skin by measuring decrease in mRNA IL-10 level at 60 to 120 mg/kg, po administered starting from day 3 post IMQ-challenge and measured 2 days post-last dose of IMQ by qPCR analysis
Organism: Mus musculus
Strain: C57
Activity Charts
Bioactivity
Activity Types for Assay ALA4618407
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 446.54 | 3.25 | 3.25 |