Binding affinity to catalytic domain of proMMP2 in human WM115 cells assessed as reduction in TIMP2-mediated inhibition of MMP2 enzyme activity at 0.1...

Basic Information

ID: ALA4618416

Type: Binding

Description: Binding affinity to catalytic domain of proMMP2 in human WM115 cells assessed as reduction in TIMP2-mediated inhibition of MMP2 enzyme activity at 0.1 nM to 1 uM incubated for 5 mins using MMP2-specific fluorogenic substrate by fluorescence based assay

Format: BAO_0000219

Organism: Homo sapiens

Target:  Matrix metalloproteinase-2(ALA333)

Document:  ALA4616672

Binding affinity to catalytic domain of proMMP2 in human WM115 cells assessed as reduction in TIMP2-mediated inhibition of MMP2 enzyme activity at 0.1 nM to 1 uM incubated for 5 mins using MMP2-specific fluorogenic substrate by fluorescence based assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
947.07-0.62-0.62