Basic Information
ID: ALA4618639
Type: Binding
Description: Inhibition of TNKS1/TNKS2 (unknown origin) expressed in HEK293 cells assessed as reduction in Wnt-signaling measured after 24 hrs by dual-glo luciferase reporter gene assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Tankyrase 1/2(ALA3038515)
Document: ALA4616677
Inhibition of TNKS1/TNKS2 (unknown origin) expressed in HEK293 cells assessed as reduction in Wnt-signaling measured after 24 hrs by dual-glo luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4618639
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 468.91 | 4.01 | 4.01 |
| 497.51 | 4.54 | 4.54 |
| 511.97 | 5.01 | 5.01 |
| 480.92 | 3.72 | 3.72 |
| 458.50 | 3.94 | 3.94 |
| 543.58 | 3.49 | 3.49 |
| 442.91 | 4.28 | 4.28 |
| 468.91 | 4.01 | 4.01 |
| 469.89 | 4.28 | 4.28 |
| 420.47 | 3.60 | 3.60 |
| 480.45 | 4.14 | 4.14 |
| 483.48 | 4.23 | 4.23 |
| 479.52 | 4.40 | 4.40 |
| 482.94 | 4.02 | 4.02 |
| 446.46 | 3.99 | 3.99 |
| 452.45 | 3.50 | 3.50 |
| 414.44 | 3.54 | 3.54 |
| 471.52 | 4.15 | 4.15 |
| 492.54 | 2.94 | 2.94 |
| 498.44 | 4.28 | 4.28 |
| 549.49 | 4.83 | 4.83 |
| 431.89 | 3.45 | 3.45 |
| 436.95 | 4.32 | 4.32 |
| 428.47 | 3.85 | 3.85 |
| 502.46 | 4.38 | 4.38 |
| 542.60 | 4.10 | 4.10 |
| 444.93 | 3.98 | 3.98 |
| 509.55 | 4.49 | 4.49 |
| 465.49 | 4.09 | 4.09 |
| 468.91 | 4.01 | 4.01 |
| 368.83 | 2.76 | 2.76 |
| 432.43 | 3.68 | 3.68 |
| 482.94 | 4.00 | 4.00 |
| 531.50 | 4.69 | 4.69 |
| 445.91 | 3.79 | 3.79 |