Basic Information
ID: ALA4618743
Type: ADME
Description: Inhibition of human CYP11B1 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycortisol as substrate by HTRF assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Cytochrome P450 11B1(ALA1908)
Document: ALA4616681
Inhibition of human CYP11B1 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycortisol as substrate by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4618743
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 212.25 | 2.64 | 2.64 |
| 232.67 | 2.99 | 2.99 |
| 232.67 | 2.99 | 2.99 |
| 223.24 | 2.21 | 2.21 |
| 244.68 | 2.90 | 2.90 |
| 383.88 | 4.36 | 4.36 |
| 235.25 | 2.11 | 2.11 |
| 258.71 | 3.46 | 3.46 |
| 383.88 | 3.84 | 3.84 |
| 334.81 | 4.68 | 4.68 |
| 355.83 | 3.41 | 3.41 |
| 258.71 | 2.94 | 2.94 |
| 264.69 | 3.15 | 3.15 |
| 210.24 | 2.24 | 2.24 |
| 237.26 | 2.23 | 2.23 |
| 272.74 | 3.85 | 3.85 |
| 369.85 | 3.45 | 3.45 |
| 395.89 | 4.36 | 4.36 |
| 369.85 | 3.97 | 3.97 |
| 391.88 | 2.82 | 2.82 |
| 270.72 | 3.38 | 3.38 |
| 286.76 | 3.67 | 3.67 |
| 395.89 | 4.36 | 4.36 |
| 383.88 | 4.36 | 4.36 |
| 276.70 | 3.08 | 3.08 |
| 272.74 | 3.63 | 3.63 |
| 397.91 | 4.75 | 4.75 |
| 272.74 | 3.33 | 3.33 |
| 260.72 | 3.32 | 3.32 |
| 369.85 | 3.80 | 3.80 |
| 355.83 | 3.41 | 3.41 |
| 272.74 | 3.50 | 3.50 |
| 284.75 | 3.85 | 3.85 |
| 383.88 | 4.36 | 4.36 |
| 369.85 | 3.97 | 3.97 |
| 405.91 | 3.21 | 3.21 |
| 397.91 | 4.75 | 4.75 |
| 383.88 | 4.36 | 4.36 |
| 250.66 | 3.13 | 3.13 |
| 246.70 | 3.30 | 3.30 |
| 405.91 | 2.86 | 2.86 |