Basic Information
ID: ALA4618783
Type: Binding
Description: Inhibition of DGKalpha/zeta in human whole blood assessed as induction of T-cell activation by measuring IFNgamma level preincubated for 1 hr followed by anti-human CD3/CD28 stimulation and measured after 24 hrs by AlphaLISA assay
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA4618783
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 509.01 | 4.63 | 4.63 |
| 519.98 | 5.04 | 5.04 |
| 499.57 | 4.77 | 4.77 |
| 467.48 | 3.23 | 3.23 |
| 499.57 | 4.77 | 4.77 |
| 543.46 | 5.28 | 5.28 |
| 499.57 | 4.77 | 4.77 |