Basic Information
ID: ALA4619091
Type: Binding
Description: Inhibition of recombinant human full length sEH (1 to 555 residues) expressed in Escherichia coli BL21 DE3 cells assessed as reduction in 6-methoxynaphthaldehyde formation using PHOME as substrate incubated for 45 mins followed by substrate addition and measured for 45 mins by fluorescence based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4619091
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 359.35 | 3.11 | 3.11 |
| 444.58 | 4.71 | 4.71 |
| 472.63 | 6.09 | 6.09 |
| 442.60 | 5.23 | 5.23 |
| 448.63 | 5.29 | 5.29 |
| 493.45 | 5.60 | 5.60 |
| 456.63 | 5.27 | 5.27 |
| 390.36 | 4.84 | 4.84 |
| 467.50 | 5.73 | 5.73 |