Basic Information
ID: ALA4619093
Type: Binding
Description: Inhibition of recombinant human full length C-terminal His6-tagged LTA4H expressed in Escherichia coli BL21 DE3 cells assessed as reduction in amino-4-methylcoumarin formation using L-arginine-7-amino-4-methylcoumarin as substrate incubated for 30 mins followed by substrate addition and measured for 30 mins by fluorescence based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4619093
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 308.38 | 0.53 | 0.53 |
| 470.66 | 5.66 | 5.66 |
| 442.60 | 5.23 | 5.23 |
| 448.63 | 5.29 | 5.29 |
| 442.60 | 4.88 | 4.88 |
| 456.63 | 5.27 | 5.27 |
| 390.36 | 4.84 | 4.84 |
| 467.50 | 5.73 | 5.73 |