Assay Report Card

Basic Information

ID: ALA4619191

Type: ADME

Description: Effect on nociception on contralateral paw in ICR mouse model of chronic constriction injury-induced neuropathic pain assessed as paw withdrawal threshold at 10 umol/kg, ip administered 7 days post-surgery and measured after 30 mins to 3 hrs post-dose by Von Frey assay

Organism: Mus musculus

Strain: ICR

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
475.517.367.36
332.284.934.93
492.505.795.79
517.557.627.62