Basic Information
ID: ALA4619368
Type: Binding
Description: Inhibition of recombinant human MLL1 complex (MLL1/Ash2L/RbBP5/WDR5/DPY-30) expressed in Escherichia coli Rosetta 2 (DE3) cells using H3 (1 to 21) peptide as substrate incubated for 1 hr in presence of 3[H] SAM by AlphaLISA assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4619368
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.42 | -1.44 | -1.44 |
| 554.65 | -0.30 | -0.30 |
| 561.04 | -0.08 | -0.08 |
| 410.44 | -2.91 | -2.91 |
| 532.65 | -0.21 | -0.21 |
| 561.04 | -0.08 | -0.08 |
| 566.62 | 0.01 | 0.01 |
| 561.04 | -0.08 | -0.08 |
| 630.75 | 1.29 | 1.29 |
| 546.67 | 0.22 | 0.22 |
| 532.63 | -0.67 | -0.67 |
| 568.68 | 0.13 | 0.13 |
| 492.58 | -1.14 | -1.14 |
| 546.67 | 0.03 | 0.03 |
| 516.56 | -1.14 | -1.14 |
| 552.60 | -0.83 | -0.83 |
| 532.63 | -0.67 | -0.67 |
| 526.60 | -0.74 | -0.74 |
| 542.64 | -0.26 | -0.26 |