Basic Information
ID: ALA4619376
Type: Binding
Description: Inhibition of PKCzeta in human THP1 cells assessed as reduction in LPS-induced TNFalpha production pre-incubated for 60 mins before LPS simulations for 4 hrs by HTRF assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: THP-1
Target: Protein kinase C zeta(ALA3438)
Document: ALA4616719
Inhibition of PKCzeta in human THP1 cells assessed as reduction in LPS-induced TNFalpha production pre-incubated for 60 mins before LPS simulations for 4 hrs by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4619376
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 350.44 | 4.18 | 4.18 |
| 330.39 | 3.52 | 3.52 |