Basic Information
ID: ALA4619486
Type: Functional
Description: In-vivo protac activity at cereblon/PDE6D in BALB/C nude mouse xenografted with human SW480 cells assessed as decrease in PDEdelta level at 50 mg/kg, ip dosed once daily for 12 consecutive days by immunofluorescence assay
Format: BAO_0000218
Organism: Mus musculus
Strain: BALB/C
Cell type: SW480
Target: Mus musculus(ALA375)
Document: ALA4616722
In-vivo protac activity at cereblon/PDE6D in BALB/C nude mouse xenografted with human SW480 cells assessed as decrease in PDEdelta level at 50 mg/kg, ip dosed once daily for 12 consecutive days by immunofluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4619486
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 457.58 | 4.21 | 4.21 |
| 722.85 | 4.26 | 4.26 |