Basic Information
ID: ALA4619535
Type: Binding
Description: Inhibition of recombinant full-length C-terminal His6-tagged Escherichia coli DNA topoisomerase 4 subunit ParC/ParE using kinetoplast DNA as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr in presence of ATP by size exclusion chromatography
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA4619535
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 331.35 | 1.58 | 1.58 |
| 361.42 | 0.83 | 0.83 |
| 360.41 | 1.92 | 1.92 |
| 329.42 | 2.96 | 2.96 |
| 373.43 | 2.66 | 2.66 |