Basic Information
ID: ALA4619594
Type: Binding
Description: Protac activity at Cereblon/BCR/ABL in human K562 cells assessed as induction of BCR-ABL degradation incubated for 32 to 48 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: K562
Activity Charts
Bioactivity
Activity Types for Assay ALA4619594
DC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1092.23 | ||
| 1004.12 | ||
| 960.07 | 4.63 | 4.63 |
| 929.34 | 3.73 | 3.73 |
| 1012.55 | ||
| 954.97 | 4.48 | 4.48 |
| 973.39 | 3.75 | 3.75 |
| 1056.60 | ||
| 1087.13 | ||
| 916.02 | 4.61 | 4.61 |
| 1017.45 | ||
| 1043.08 | ||
| 968.50 | 4.01 | 4.01 |
| 880.39 | 3.98 | 3.98 |
| 924.44 | 3.99 | 3.99 |
| 1061.50 | ||
| 999.02 | 4.50 | 4.50 |
| 1131.18 | ||
| 1048.17 | ||
| 885.29 | 3.71 | 3.71 |