Basic Information
ID: ALA4619598
Type: Binding
Description: Protac activity at Cereblon/BCR/ABL T315I mutant (unknown origin) expressed in mouse BaF3 cells assessed as reduction in BCR-ABL T315I mutant driven cell viability incubated for 3 days by CCK8 assay
Organism: Homo sapiens
Cell type: BaF3
Activity Charts
Bioactivity
Activity Types for Assay ALA4619598
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 488.02 | 3.31 | 3.31 |
| 532.57 | 4.46 | 4.46 |
| 449.85 | 3.46 | 3.46 |
| 1005.17 | ||
| 490.61 | 4.75 | 4.75 |
| 508.60 | 4.89 | 4.89 |
| 1056.60 | ||
| 1087.13 | ||
| 1017.45 | ||
| 384.51 | 2.75 | 2.75 |
| 490.61 | 4.75 | 4.75 |
| 1001.61 | ||
| 502.64 | 4.62 | 4.62 |
| 508.60 | 4.89 | 4.89 |
| 488.62 | 4.31 | 4.31 |
| 486.65 | 4.92 | 4.92 |