Assay Report Card

Basic Information

ID: ALA4619602

Type: Binding

Description: Protac activity at Cereblon/BCR/ABL T315I mutant (unknown origin) expressed in mouse BaF3 cells assessed as reduction in BCR-ABL T315I mutant protein levels at 3 to 30000 nM incubated for 48 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: BaF3

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1005.17
1056.60
1001.61