Assay Report Card

Basic Information

ID: ALA4619612

Type: Binding

Description: Protac activity at Cereblon/BCR/ABL in human K562 cells assessed as synergistic antiproliferation effect by measuring combination index at 0.25 to 4 times alone antiproliferative EC50 ibn presence of hedgehog pathway inhibitor GDC-044 by Chou-Talalay method

Organism: Homo sapiens

Cell type: K562

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1087.13