Basic Information
ID: ALA4620552
Type: Binding
Description: Inhibition of GFP-tagged KRAS G12V mutant (unknown origin) expressed in MDCK cells cotransfected with mCherry-CAXX assessed as increase in KRAS G12V-plasma membrane dissociation incubated for 48 hrs by quantitative confocal microscopic method
Organism: Homo sapiens
Cell type: MDCK
Activity Charts
Bioactivity
Activity Types for Assay ALA4620552
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 341.41 | 3.67 | 3.67 |
| 343.34 | 3.52 | 3.52 |
| 316.33 | 3.75 | 3.75 |
| 328.36 | 3.62 | 3.62 |
| 313.35 | 3.19 | 3.19 |
| 377.23 | 4.37 | 4.37 |
| 343.34 | 3.52 | 3.52 |
| 299.33 | 3.00 | 3.00 |
| 334.32 | 3.89 | 3.89 |
| 334.32 | 3.89 | 3.89 |