Basic Information
ID: ALA4620714
Type: Binding
Description: Activation of PXR (unknown origin) at 5 uM relative to control
Format: BAO_0000357
Organism: Homo sapiens
Target: Pregnane X receptor(ALA3401)
Document: ALA4619752
Activation of PXR (unknown origin) at 5 uM relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4620714
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 643.54 | 4.61 | 4.61 |
| 663.54 | 4.81 | 4.81 |
| 645.55 | 4.86 | 4.86 |
| 701.59 | 5.61 | 5.61 |
| 656.51 | 4.91 | 4.91 |
| 679.52 | 4.86 | 4.86 |
| 681.53 | 5.11 | 5.11 |
| 649.10 | 5.00 | 5.00 |
| 635.53 | 5.49 | 5.49 |
| 741.54 | 5.45 | 5.45 |
| 645.55 | 4.72 | 4.72 |
| 619.51 | 4.33 | 4.33 |
| 645.55 | 4.72 | 4.72 |
| 645.55 | 4.52 | 4.52 |
| 657.56 | 4.86 | 4.86 |
| 704.60 | 4.37 | 4.37 |
| 647.57 | 5.11 | 5.11 |
| 687.51 | 5.26 | 5.26 |
| 633.54 | 4.72 | 4.72 |
| 607.56 | 4.02 | 4.02 |
| 673.49 | 4.87 | 4.87 |
| 643.13 | 4.47 | 4.47 |
| 649.52 | 4.42 | 4.42 |
| 632.65 | 4.49 | 4.49 |
| 663.54 | 4.81 | 4.81 |
| 619.51 | 4.33 | 4.33 |
| 658.53 | 5.20 | 5.20 |
| 721.60 | 4.18 | 4.18 |
| 649.52 | 4.42 | 4.42 |
| 663.54 | 4.81 | 4.81 |
| 577.41 | 4.02 | 4.02 |
| 667.51 | 4.72 | 4.72 |
| 655.50 | 4.57 | 4.57 |
| 631.53 | 4.47 | 4.47 |
| 677.57 | 5.20 | 5.20 |
| 677.57 | 5.06 | 5.06 |
| 680.64 | 4.88 | 4.88 |
| 631.53 | 4.47 | 4.47 |
| 645.55 | 4.86 | 4.86 |
| 663.54 | 4.81 | 4.81 |
| 631.53 | 4.47 | 4.47 |
| 667.51 | 4.72 | 4.72 |
| 658.69 | 5.02 | 5.02 |
| 691.60 | 5.45 | 5.45 |
| 647.57 | 4.96 | 4.96 |
| 629.51 | 3.94 | 3.94 |
| 666.61 | 4.49 | 4.49 |
| 633.54 | 4.72 | 4.72 |
| 633.54 | 4.72 | 4.72 |
| 653.48 | 4.33 | 4.33 |
| 649.52 | 5.02 | 5.02 |
| 649.52 | 4.42 | 4.42 |
| 723.62 | 4.62 | 4.62 |
| 617.50 | 4.08 | 4.08 |
| 645.55 | 4.86 | 4.86 |
| 657.56 | 4.86 | 4.86 |