Basic Information
ID: ALA4620717
Type: Functional
Description: In vivo inhibition of RORgammat in mouse assessed as inhibition of anti-CD3/anti-CD28 monoclonal antibodies/IL-23-stimulated IL-17A production in blood at 3 mg/kg, po followed by ex vivo stimulation of anti-CD3/anti-CD28 monoclonal antibodies/IL-23 measured after 1 hr of compound administration by ELISA relative to control
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4620717
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 649.52 | 4.42 | 4.42 |