Basic Information
ID: ALA4620718
Type: Functional
Description: In vivo inhibition of RORgammat in mouse assessed as inhibition of anti-CD3/anti-CD28 monoclonal antibodies/IL-23-stimulated IL-17A production in blood at 30 mg/kg, po followed by ex vivo stimulation of anti-CD3/anti-CD28 monoclonal antibodies/IL-23 measured after 4 hrs of compound administration by ELISA relative to control
Format: BAO_0000218
Organism: Mus musculus
Target: Nuclear receptor ROR-gamma(ALA1293231)
Document: ALA4619752
In vivo inhibition of RORgammat in mouse assessed as inhibition of anti-CD3/anti-CD28 monoclonal antibodies/IL-23-stimulated IL-17A production in blood at 30 mg/kg, po followed by ex vivo stimulation of anti-CD3/anti-CD28 monoclonal antibodies/IL-23 measured after 4 hrs of compound administration by ELISA relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4620718
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 649.52 | 4.42 | 4.42 |