Basic Information
ID: ALA4620829
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in LPS-stimulated human THP1 cells assessed as IL-1beta secretion at 10 uM incubated for 1 hr followed by nigericin addition and measured after 1 hr by ELISA relative to control
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA4620829
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 314.47 | 5.85 | 5.85 |
| 404.49 | 2.99 | 2.99 |
| 364.44 | 0.38 | 0.38 |