Basic Information
ID: ALA4621379
Type: Binding
Description: Inhibition of human F11a using D-Leu-Pro-Arg*Rh110-D-Pro as substrate preincubated for 60 mins followed by substrate addition and measured after 60 mins by fluorescence assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Coagulation factor XI(ALA2820)
Document: ALA4619774
Inhibition of human F11a using D-Leu-Pro-Arg*Rh110-D-Pro as substrate preincubated for 60 mins followed by substrate addition and measured after 60 mins by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4621379
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 347.41 | 4.02 | 4.02 |
| 360.41 | 3.69 | 3.69 |
| 431.53 | 5.50 | 5.50 |
| 442.56 | 5.17 | 5.17 |
| 445.52 | 4.62 | 4.62 |
| 442.52 | 4.75 | 4.75 |
| 463.53 | 4.69 | 4.69 |
| 456.54 | 5.26 | 5.26 |
| 373.45 | 4.21 | 4.21 |
| 433.50 | 4.18 | 4.18 |
| 431.53 | 4.43 | 4.43 |
| 416.52 | 5.22 | 5.22 |
| 461.95 | 4.37 | 4.37 |
| 460.53 | 3.71 | 3.71 |
| 444.53 | 5.04 | 5.04 |
| 417.51 | 5.08 | 5.08 |
| 451.95 | 5.84 | 5.84 |
| 447.53 | 5.20 | 5.20 |
| 458.56 | 4.66 | 4.66 |
| 459.54 | 5.01 | 5.01 |
| 417.51 | 5.19 | 5.19 |
| 456.54 | 5.26 | 5.26 |
| 375.42 | 3.95 | 3.95 |