Assay Report Card

Basic Information

ID: ALA4621836

Type: Binding

Description: Inhibition of caspase-1 activity in LPS-primed immortalized mouse J744A.1 cells assessed as reduction in nigericin-induced Ac-YVAD-pNA cleavage using Ac-YVAD-pNA as substrate at 5 uM by FAM-FLICA reagent based confocal microscopy

Organism: Mus musculus

Cell type: J774.A1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
580.635.345.34