Assay Report Card

Basic Information

ID: ALA4622181

Type: Functional

Description: In vivo modulation of gamma secretase in APP-Swedish transgenic mouse assessed as reduction in Abeta42 production by measuring remaining Abeta42 level at 1 mg/kg, po measured after 4 hrs by ELISA or AlphaLISA assay relative to control

Organism: Mus musculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
438.483.763.76
439.473.163.16
471.514.304.30