Basic Information
ID: ALA4622182
Type: Functional
Description: In vivo modulation of gamma secretase in APP-Swedish transgenic mouse assessed as reduction in Abeta42 production by measuring remaining Abeta42 level at 3 mg/kg, po measured after 4 hrs by ELISA or AlphaLISA assay relative to control
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4622182
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.48 | 3.76 | 3.76 |
| 439.47 | 3.16 | 3.16 |
| 481.45 | 4.30 | 4.30 |
| 471.51 | 4.30 | 4.30 |