Basic Information
ID: ALA4622283
Type: Binding
Description: Inhibition of human Notum (S81 to T451 residues) Cys330Ser mutant expressed in HEK293S GnTI cells using OPTS as substrate incubated for 40 mins by fluorescence based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4622283
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 111.10 | 0.71 | 0.71 |
| 125.13 | 1.02 | 1.02 |
| 215.25 | 2.79 | 2.79 |
| 229.28 | 2.85 | 2.85 |
| 179.22 | 2.14 | 2.14 |
| 233.24 | 2.93 | 2.93 |
| 229.28 | 3.10 | 3.10 |
| 245.28 | 2.80 | 2.80 |
| 279.72 | 3.45 | 3.45 |
| 346.78 | 3.81 | 3.81 |
| 350.77 | 2.95 | 2.95 |
| 205.26 | 1.91 | 1.91 |
| 293.67 | 3.27 | 3.27 |
| 209.22 | 1.74 | 1.74 |
| 229.28 | 3.10 | 3.10 |
| 259.23 | 2.62 | 2.62 |
| 293.67 | 3.27 | 3.27 |
| 257.33 | 3.92 | 3.92 |
| 375.78 | 2.44 | 2.44 |
| 233.24 | 2.93 | 2.93 |
| 389.81 | 2.49 | 2.49 |
| 267.69 | 3.58 | 3.58 |
| 260.12 | 2.90 | 2.90 |
| 274.71 | 3.32 | 3.32 |
| 125.13 | 1.02 | 1.02 |
| 153.18 | 1.34 | 1.34 |
| 362.78 | 3.04 | 3.04 |
| 293.67 | 3.27 | 3.27 |
| 283.25 | 3.81 | 3.81 |
| 284.14 | 4.10 | 4.10 |
| 255.32 | 3.67 | 3.67 |
| 179.10 | 1.73 | 1.73 |
| 273.31 | 3.81 | 3.81 |
| 283.25 | 3.56 | 3.56 |
| 284.14 | 4.10 | 4.10 |
| 259.31 | 3.19 | 3.19 |
| 306.72 | 2.93 | 2.93 |
| 191.23 | 1.60 | 1.60 |
| 215.25 | 2.54 | 2.54 |
| 294.56 | 3.56 | 3.56 |
| 277.22 | 2.76 | 2.76 |
| 275.23 | 2.50 | 2.50 |
| 284.14 | 4.10 | 4.10 |
| 260.12 | 2.90 | 2.90 |
| 225.68 | 2.25 | 2.25 |
| 225.68 | 2.25 | 2.25 |
| 333.70 | 3.03 | 3.03 |
| 368.79 | 4.82 | 4.82 |
| 240.26 | 2.66 | 2.66 |
| 368.73 | 3.66 | 3.66 |
| 260.12 | 2.90 | 2.90 |
| 317.69 | 4.46 | 4.46 |
| 277.22 | 2.76 | 2.76 |
| 193.12 | 2.04 | 2.04 |
| 233.24 | 2.93 | 2.93 |
| 225.68 | 2.25 | 2.25 |
| 284.14 | 4.10 | 4.10 |
| 271.36 | 4.09 | 4.09 |
| 216.24 | 1.47 | 1.47 |
| 260.12 | 2.90 | 2.90 |
| 249.70 | 3.45 | 3.45 |
| 139.15 | 1.33 | 1.33 |
| 320.74 | 3.27 | 3.27 |
| 284.14 | 4.10 | 4.10 |
| 201.22 | 2.48 | 2.48 |
| 388.82 | 3.29 | 3.29 |
| 139.15 | 1.33 | 1.33 |
| 258.25 | 2.80 | 2.80 |
| 229.28 | 3.10 | 3.10 |
| 249.70 | 3.45 | 3.45 |
| 260.12 | 2.90 | 2.90 |
| 259.23 | 2.62 | 2.62 |
| 275.32 | 4.05 | 4.05 |
| 284.14 | 4.10 | 4.10 |
| 293.67 | 3.27 | 3.27 |
| 233.31 | 2.72 | 2.72 |
| 317.69 | 4.46 | 4.46 |
| 193.25 | 2.21 | 2.21 |
| 209.22 | 1.74 | 1.74 |
| 269.22 | 3.50 | 3.50 |
| 249.70 | 3.45 | 3.45 |
| 317.70 | 3.74 | 3.74 |
| 125.13 | 1.02 | 1.02 |
| 260.12 | 2.90 | 2.90 |