Basic Information
ID: ALA4622293
Type: Binding
Description: Inhibition of MRS4174 binding to human P2Y14R expressed in CHO cells pre-incubated for 30 mins before MRS4174 addition and further incubated for 30 mins at pH 7.4 by flow cytomtery based competitive fluorescence assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA4622293
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 555.64 | 8.87 | 8.87 |
| 479.46 | 5.02 | 5.02 |
| 897.00 | 7.24 | 7.24 |
| 428.37 | 4.42 | 4.42 |
| 467.40 | 4.90 | 4.90 |
| 504.51 | 5.57 | 5.57 |
| 414.43 | 5.53 | 5.53 |
| 513.56 | 7.70 | 7.70 |
| 473.50 | 5.96 | 5.96 |
| 481.48 | 5.11 | 5.11 |
| 516.58 | 7.77 | 7.77 |
| 575.63 | 9.01 | 9.01 |
| 452.39 | 4.42 | 4.42 |
| 428.37 | 4.42 | 4.42 |
| 473.49 | 7.27 | 7.27 |
| 468.39 | 4.30 | 4.30 |
| 501.55 | 7.63 | 7.63 |
| 517.59 | 8.48 | 8.48 |
| 493.49 | 4.73 | 4.73 |
| 518.54 | 6.06 | 6.06 |
| 509.49 | 4.40 | 4.40 |
| 955.08 | 8.63 | 8.63 |
| 559.67 | 9.65 | 9.65 |
| 540.49 | 5.81 | 5.81 |
| 467.40 | 4.90 | 4.90 |
| 825.92 | 7.73 | 7.73 |
| 491.52 | 5.19 | 5.19 |
| 854.96 | 7.06 | 7.06 |
| 489.54 | 7.70 | 7.70 |