Assay Report Card

Basic Information

ID: ALA4622644

Type: Binding

Description: Inhibition of AKR1C3 in human 22Rv1 cells assessed as as reduction in AR mRNA expression at 10 to 20 uM pre-incubated for 2 hrs before pregnenolone stimulation for 24 hrs by RT-qPCR analysis

Organism: Homo sapiens

Cell type: CWR22R

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
298.273.013.01
294.313.183.18