Basic Information
ID: ALA4622645
Type: Binding
Description: Inhibition of AKR1C3 in human 22Rv1 cells assessed as as reduction in TMPRSS2 mRNA expression at 10 to 20 uM pre-incubated for 2 hrs before pregnenolone stimulation for 24 hrs by RT-qPCR analysis
Organism: Homo sapiens
Cell type: CWR22R
Activity Charts
Bioactivity
Activity Types for Assay ALA4622645
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 298.27 | 3.01 | 3.01 |
| 294.31 | 3.18 | 3.18 |