Basic Information
ID: ALA4622683
Type: Binding
Description: Inhibition of AKR1C3 in human 22Rv1 cells assessed as potentiation of abiraterone-induced apoptosis by measuring increase in cleaved PARP level at 10 uM pre-incubated for 2 hrs before addition of pregnenolone for 24 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: CWR22R
Activity Charts
Bioactivity
Activity Types for Assay ALA4622683
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 298.27 | 3.01 | 3.01 |
| 294.31 | 3.18 | 3.18 |