Basic Information
ID: ALA4622743
Type: Binding
Description: Antagonist activity at human TLR3 overexpressed in HEK-Blue cells assessed as inhibition of Poly IC-induced NFkappaB and AP-1 activation preincubated for 30 mins followed by Poly IC stimulation measured after 22 hrs by quanti-blue SEAP assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Toll-like receptor 3(ALA1075113)
Document: ALA4619828
Antagonist activity at human TLR3 overexpressed in HEK-Blue cells assessed as inhibition of Poly IC-induced NFkappaB and AP-1 activation preincubated for 30 mins followed by Poly IC stimulation measured after 22 hrs by quanti-blue SEAP assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4622743
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 435.61 | 5.37 | 5.37 |
| 407.56 | 4.56 | 4.56 |