Basic Information
ID: ALA4623530
Type: Binding
Description: Inhibition of calf thymus Top1 assessed as reduction in supercoiled pBR322 DNA relaxation at 100 uM measured after 30 mins by agarose gel electrophoresis relative to camptothecin
Organism: Bos taurus
Activity Charts
Bioactivity
Activity Types for Assay ALA4623530
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.71 | 7.23 | 7.23 |
| 256.26 | 2.70 | 2.70 |
| 270.28 | 3.00 | 3.00 |
| 472.71 | 6.20 | 6.20 |
| 472.71 | 6.06 | 6.06 |
| 488.71 | 5.18 | 5.18 |
| 442.73 | 7.00 | 7.00 |
| 498.75 | 7.66 | 7.66 |
| 454.70 | 7.30 | 7.30 |
| 488.71 | 5.18 | 5.18 |
| 488.71 | 5.18 | 5.18 |
| 302.46 | 4.52 | 4.52 |
| 388.55 | 5.06 | 5.06 |
| 546.79 | 5.93 | 5.93 |
| 316.44 | 3.63 | 3.63 |
| 318.46 | 3.10 | 3.10 |
| 316.44 | 4.61 | 4.61 |
| 488.71 | 5.79 | 5.79 |
| 302.46 | 4.52 | 4.52 |
| 454.70 | 6.54 | 6.54 |
| 302.46 | 4.52 | 4.52 |
| 648.88 | 8.18 | 8.18 |
| 514.75 | 6.78 | 6.78 |
| 316.44 | 4.61 | 4.61 |
| 314.43 | 3.84 | 3.84 |
| 502.74 | 6.44 | 6.44 |
| 316.44 | 3.63 | 3.63 |