Assay Report Card

Basic Information

ID: ALA4623538

Type: Binding

Description: Inhibition of calf thymus Top1-mediated supercoiled pBR322 DNA cleavage assessed as nicked DNA content at 25 uM measured after 30 mins by ethidium bromide staining agarose gel electrophoresis (Rvb = 15%)

Organism: Bos taurus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
348.362.082.08
454.707.307.30
388.555.065.06
648.888.188.18