Basic Information
ID: ALA4623539
Type: Binding
Description: Inhibition of calf thymus Top1-mediated supercoiled pBR322 DNA cleavage assessed as nicked DNA content at 50 uM measured after 30 mins by ethidium bromide staining agarose gel electrophoresis (Rvb = 15%)
Organism: Bos taurus
Activity Charts
Bioactivity
Activity Types for Assay ALA4623539
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.36 | 2.08 | 2.08 |
| 454.70 | 7.30 | 7.30 |
| 388.55 | 5.06 | 5.06 |
| 648.88 | 8.18 | 8.18 |